Clinical Standards of Excellence

Skin and Sarcoma Oncology Division

Division Co-Chiefs:  Andrew L. Pecora, MD, James Wittig, MD

Quality Indicators (Medical/Surgical/Radiation):

  1. Initial diagnostic work-up is at 95% compliance
  2. All melanoma patients with node positive disease are offered adjuvant therapy.
  3. Documentation that all patients with skin cancer have been taught how to do a self skin exam.

All Patients

  1. All patients with solid tumors are staged according to ACoS standards.
  2. All patients who are receiving chemotherapy have a plan documented prior to administration of therapy.

Diagnostic Work Up:

Invasive Melanoma of Skin
ICD 9 Codes
172.0
172.1
172.2
172.3
172.4
172.5
172.6
172.7
172.8
172.9
Diagnostic Work Up (4 Scenarios)

1.  Lesion < 0.75mm deep

Exam/Test

Wide excision only

Pathology review

Chest x-ray

Chemistry panel

2.  Lesion is 0.75mm deep, but < 1.0mm deep

Exam/Test

Good Risk: No adverse features

Wide excision only

Pathology review

Chest x-ray

Chemistry panel

Poor Risk: Ulceration, Clarks level IV, Signs of regression, Marked pleomorphism, or Shave biopsy

Wide excision with sentinel node biopsy

Pathology review

PET/CT Scan

MRI Brain with and without gadolinium

Chemistry panel

3.  Lesion > 1.0mm deep

Exam/Test

Wide excision with sentinel node biopsy

Pathology review

PET/CT Scan

MRI Brain with and without gadolinium

Chemistry Panel

4.  Metastases on presentation

Exam/Test

PET/CT Scan

MRI Brain with and without gadolinium

Chemistry panel

Prognostic Work Up
Uveal Melanoma
ICD 9 Codes
190.0
Diagnostic Work Up

1.  Small

Exam/Test

Radiation plaque therapy

PET/CT Scan

MRI Brain with and without gadolinium

2.  Large

Exam/Test

Enucleation

PET/CT Scan

MRI Brain with and without gadolinium

MRI Liver with and without gadolinium (if PET/CT equivocal)

Prognostic Work Up
Invasive Squamous Cell Cancer
ICD 9 Codes
173.0
173.1
173.2
173.3
173.4
173.5
173.6
173.7
173.8
173.9
Diagnostic Work Up
Test/Exam:

CT Chest

Chemistry panel

Prognostic Work Up
Bone Cancer
ICD 9 Codes
170.0
170.1
170.2
170.3
170.4
170.5
170.6
170.7
170.8
170.9
238.0
198.5
195.3
195.4
195.5
195.8
202.9
198.89
239.2
Diagnostic Work Up
Test/Exam:

History and Physical Examination

CBC

Chem 20

PT/PTT

CRP

ESR

SPEP (Serum Protein Electrophoresis; suspected myeloma)

Xrays of Extremity

MRI of Bone/Extremity with gadolinium

CT of Bone and Extremity +/- contrast

Whole Body Bone Scan

CT Chest +/- Contrast

CT Abdomen and Pelvis +/- contrast

PET/CT Scan whole body:

~ May be substituted in lieu of CT Chest, Abdomen and Pelvis

~ Necessary in cases of multicentric tumors or tumors with unusual patterns of metastases

Thallium Scan (Osteosarcoma)

Pathologic Review:

~ Cytogenetics

~ Immunostains (Panel)

~ Routine Histology

~ Ewing’s Sarcoma Translocation: t11;22 t21;22 t7;22 t17;22 t2;22

~ Osteosarcoma: Her-2/neu gene, Retinoblastoma gene, P53 gene

~ Small Cell Osteosarcoma: t11;22

~ Lymphoma of Bone: Flow Cytometry

~ Eosinophilic Granuloma: Electron Microscopy

Prognostic Work Up
Soft Tissue Cancer
ICD 9 Codes
171.0
171.2
171.3
171.4
171.5
171.6
171.7
171.8
171.9
238.1
176.1
239.2
Diagnostic Work Up
Test/Exam:

History and Physcial Examination

Xrays of Site

MRI of Site/Extremity with gadolinium

CT of Site/Extremity +/- contrast

CT Chest, Abdomen, Pelvis with contrast

PET/CT Scan whole body for specific tumors with unusual patterns of metastases (substitute for CT Chest, Abdomen, Pelvis)

Whole Body Bone Scan

Pathologic Review:

~ Cytogenetics

~ Immunostains (Panel)

~ Routine Histology

~ Liposarcoma: Myxoid/Round Cell Type: t12;16

~ Synovial Sarcoma: tX;18 (SYT-SSX)

~ Soft Tissue Ewing’s Sarcoma : t11;22 t21;22 t7;22 t17;22 t2;22

~ Soft Tissue Osteosarcoma: Her2-neu, RB gene, p53 gene

~ Rhabdomyosarcoma: t2;13 t1;13 PAX3/FKHR Fusion Gene

~ Vascular Tumors: VEGFR-3

~ Clear Cell Sarcoma: t12;22

Prognostic Work Up
Other Skin Cancer
ICD 9 Codes
173.0
173.1
173.2
173.3
173.4
173.5
173.6
173.7
173.8
173.9
238.2
239.2
Diagnostic Work Up
Test/Exam:

History and Physcial Examination

PET/CT Scan whole body

Pathologic Review:

~ Routine Histology

~ Cytogenetics

~ Immunohistochemistry

Prognostic Work Up
Kaposi's Sarcoma
ICD 9 Codes
176.0
176.1
176.2
176.3
176.4
176.5
176.8
176.9
Diagnostic Work Up
Test/Exam:

History and Physcial Examination

PET/CT Scan whole body

Pathologic Review:

~ Routine Histology

~ Cytogenetics

~ Immunohistochemistry

Prognostic Work Up
Skin in Situ
ICD 9 Codes
232.0
232.1
232.2
232.3
232.4
232.5
232.6
232.7
232.8
232.9
238.2
Diagnostic Work Up
Test/Exam:

History and Physcial Examination

PET/CT Scan whole body

Pathologic Review:

~ Routine Histology

~ Cytogenetics

~ Immunohistochemistry

Prognostic Work Up
Last updated: 2010-07-30